Computational Hemodynamics of an Implanted Coronary Stent Based on Three-Dimensional Cine Angiography Reconstruction
學年 94
學期 1
出版（發表）日期 2005-08-01
作品名稱 Computational Hemodynamics of an Implanted Coronary Stent Based on Three-Dimensional Cine Angiography Reconstruction
作品名稱（其他語言）
著者 Chen, Mounter C. Y.; Lu, Po-Chien; Chen, James S. Y.; Hwang, Ned H. C.
單位 淡江大學水資源及環境工程學系
出版者 PA: Lippincott Williams & Wilkins
著錄名稱、卷期、頁數 ASAIO Journal 51(4), pp.313-320
摘要 Coronary stents are supportive wire meshes that keep narrow coronary arteries patent, reducing the risk of restenosis. Despite the common use of coronary stents, approximately 20-35% of them fail due to restenosis. Flow phenomena adjacent to the stent may contribute to restenosis. Three-dimensional computational fluid dynamics (CFD) and reconstruction based on biplane cine angiography were used to assess coronary geometry and volumetric blood flows. A patient-specific left anterior descending (LAD) artery was reconstructed from single-plane x-ray imaging. With corresponding electrocardiographic signals, images from the same time phase were selected from the angiograms for dynamic three-dimensional reconstruction. The resultant three-dimensional LAD artery at end-diastole was adopted for detailed analysis. Both the geometries and flow fields, based on a computational model from CAE software (ANSYS and CATIA) and full three-dimensional Navier-Stroke equations in the CFD-ACE+ software, respectively, changed dramatically after stent placement. Flow fields showed a complex three-dimensional spiral motion due to arterial tortuosity. The corresponding wall shear stresses, pressure gradient, and flow field all varied significantly after stent placement. Combined angiography and CFD techniques allow more detailed investigation of flow patterns in various segments. The implanted stent(s) may be quantitatively studied from the proposed hemodynamic modeling approach.
關鍵字
語言 en
ISSN 1058-2916
期刊性質 國外
收錄於 SCI EI
產學合作
通訊作者
審稿制度
國別 USA
公開徵稿
出版型式 紙本
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