Is Liver Cirrhosis a Risk Factor for Osteonecrosis of the Femoral Head in Adults? A Population-Based 3-Year Follow-Up Study
學年 100
學期 1
出版（發表）日期 2011-11-01
作品名稱 Is Liver Cirrhosis a Risk Factor for Osteonecrosis of the Femoral Head in Adults? A Population-Based 3-Year Follow-Up Study
作品名稱（其他語言）
著者 Hung, Tsung-Hsing; Hsieh, Yu-Hsi, Tsai, Chih-Chun, Tseng, Chih-Wei, Tseng, Kuo-Chih, Tsai, Chen-Chi
單位 淡江大學數學學系
出版者 Tokyo: The Japanese Society of Internal Medicine
著錄名稱、卷期、頁數 Internal Medicine 50(21), pp.2563-2568
摘要 Background. The relationship between osteonecrosis of the femoral head (OFH) and liver cirrhosis is controversial. The aim of this study was to determine whether liver cirrhosis is associated with the occurrence of OFH. Methods. We used the National Health Insurance Database, derived from the Taiwan National Health Insurance program. The study cohort comprised 40,769 adult patients with liver cirrhosis. The comparison cohort consisted of 40,769 randomly selected age- and sex-matched subjects. Results. During the 3-year follow-up period, there were 321 (0.8%) cirrhotic patients with OFH, and 126 (0.3%) non-cirrhotic patients with OFH (p<0.001). Cox's regression analysis, adjusted by the patients' age, sex, and other confounding factors, showed that the cirrhotic patients had a higher risk for occurrence of OFH than non-cirrhotic patients during the 3-year period (hazard ratio=2.38, p<0.001). In this 3-year study, the incidence density of cirrhotic patients hospitalized for OFH was 3 episodes/1,000 person-year. Conclusion. We conclude that cirrhotic patients have a higher risk for occurrence of OFH than non-cirrhotic patients.
關鍵字 osteonecrosis; femoral head; liver cirrhosis
語言 en
ISSN 0918-2918; 1349-7235
期刊性質 國外
收錄於 SCI
產學合作
通訊作者 Tsai, Chen-Chi
審稿制度
國別 JPN
公開徵稿
出版型式 紙本
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SDGS 良好健康和福祉