Calcium phosphates synthesized by reverse emulsion method for the preparation of chitosan composite membranes
學年 100
學期 2
出版（發表）日期 2012-04-15
作品名稱 Calcium phosphates synthesized by reverse emulsion method for the preparation of chitosan composite membranes
作品名稱（其他語言）
著者 Tai, Hung-Yin; Fu, Earl; Don, Trong-Ming
單位 淡江大學化學工程與材料工程學系
出版者 Pergamon: Pergamon
著錄名稱、卷期、頁數 Carbohydrate Polymers 88(3), pp.904–911
摘要 Calcium deficient hydroxyapatite (CDHA) having an average particle size of 45 nm was synthesized by reverse emulsion method. It was converted to the respective biphasic calcium phosphate (BCP, 226 nm) and β-tricalcium phosphate (TCP, 450 nm) by calcination at 800 °C and 1000 °C, and the BCP consisted of 92% TCP and 8% CDHA. Subsequently, chitosan was mixed with calcium phosphates to prepare CDHA/chitosan, BCP/chitosan, and TCP/chitosan membranes. The initial moduli of the BCP/chitosan and TCP/chitosan membranes were about 1.9 times that of the pure chitosan membrane; and the elongations at break were almost 6 times. The CDHA/chitosan and BCP/chitosan could induce mineralization of apatite on the membranes by increasing 20.6 and 16.3 wt.%, respectively, after 24 days in the simulated body fluid. Moreover, the BCP/chitosan exhibited superior osteoblast cell attachment and proliferation than the other membranes. It has the potential to be used as the barrier membrane for guided bone regeneration.
關鍵字 Chitosan;Calcium phosphate;Composite membranes
語言 en
ISSN 1879-1344
期刊性質 國外
收錄於 SCI
產學合作
通訊作者 Don, Trong-Ming
審稿制度 否
國別 GBR
公開徵稿
出版型式 ,電子版,紙本
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