| 標題：Effect of cell membrane structure of human erythrocyte on its electrophoresis |
|---|
| 學年 | 92 |
|---|
| 學期 | 1 |
|---|
| 出版（發表）日期 | 2003/11/01 |
|---|
| 作品名稱 | Effect of cell membrane structure of human erythrocyte on its electrophoresis |
|---|
| 作品名稱（其他語言） | |
|---|
| 著者 | Hsu, Jyh-ping; Lin, Sung-hwa; 曾琇瑱; Tseng, Shio-jenn |
|---|
| 單位 | 淡江大學數學學系 |
|---|
| 出版者 | Elsevier |
|---|
| 著錄名稱、卷期、頁數 | Colloids and Surfaces B: Biointerfaces 32(3), pp.203-212 |
|---|
| 摘要 | The electrophoretic behavior of human erythrocyte is investigated theoretically. The present analysis extends previous studies to that the effect of the membrane structure of a cell is taken into account. The result obtained provides a useful tool for the estimation of the surface properties of human erythrocyte through electrophoretic measurements. Fitting the present model to the experimental data of Haydon and Seaman [Arch. Biochem. Biophys. 122 (1967) 126], for example, reveals that the surface charge of erythrocyte arises mainly from the dissociation of three functional groups, which bond to different sites on cell membrane : (a) N-acetylneuraminic acid (sialic acid) with pKHANaa=2.6, (b) some kind of α-carboxylic acid with pKHAα−ca=3.35, (c) weak amino base functional group with pKBH+=8.5. The distribution of Na+ in the protein layer of a cell is found to vary with the pH of the bulk liquid phase, the possible implication of this phenomenon to cell physiology is discussed. |
|---|
| 關鍵字 | Cell membrane structure;Human erythrocyte;Electrophoresis;Mathematical model |
|---|
| 語言 | 英文 |
|---|
| ISSN | 0927-7765 |
|---|
| 期刊性質 | 國內 |
|---|
| 收錄於 | |
|---|
| 產學合作 | |
|---|
| 通訊作者 | |
|---|
| 審稿制度 | 否 |
|---|
| 國別 | 中華民國 |
|---|
| 公開徵稿 | |
|---|
| 出版型式 | ,電子版 |
|---|
| 相關連結 | |
|---|
|
Google+ 推薦功能，讓全世界都能看到您的推薦！
