教師資料查詢 | 類別: 期刊論文 | 教師: 施增廉 SHIH, TZENGE-LIEN (瀏覽個人網頁)

標題:Synthesis of a New Family of Aminocyclitols from D-(-)-Quinic acid
學年96
學期1
出版(發表)日期2008/01/01
作品名稱Synthesis of a New Family of Aminocyclitols from D-(-)-Quinic acid
作品名稱(其他語言)
著者Shih, Tzenge-lien; Li, Heng-Yi; Ke, Ming-Shin; Kuo, Wei-Shen
單位淡江大學化學學系
出版者Philadelphia: Taylor & Francis Inc.
著錄名稱、卷期、頁數Synthetic Communications 38(23), pp.4139-4149
摘要In continuation of our interest in the synthesis of glycosidase inhibitors, we report herein an efficient synthesis of three new polyhydroxylated amino cyclohexane derivatives (aminocyclitols) that may potentially possess important biological activities. The key step involved the highly stereoselective dihydroxylation of protected azido cyclohexene derivatives 5, 9, and 15, which were easily red from D-(-)-quinic acid. The subsequent hydrogenation step was conducted under acidic conditions to provide the target molecules in an efficient manner with high overall yields.
關鍵字
語言英文
ISSN0039-7911; 1532-2432
期刊性質國外
收錄於SCI
產學合作
通訊作者
審稿制度
國別美國
公開徵稿
出版型式紙本
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