期刊論文
| 學年 | 114 |
|---|---|
| 學期 | 1 |
| 出版（發表）日期 | 2025-08-20 |
| 作品名稱 | Design of a General Type BSSO Fixation Plate Integrating Topology and Parameter Optimization for Various Severity Levels of Hemifacial Microsomia |
| 作品名稱（其他語言） | |
| 著者 | Chun-Ming Chang; Po-Fang Wang; Yu-Tzu Wang |
| 單位 | |
| 出版者 | |
| 著錄名稱、卷期、頁數 | Frontiers in Bioengineering and Biotechnology-Biomechanics 13, 1598975 |
| 摘要 | Introduction: Patients with hemifacial microsomia exhibit varying degrees of mandibular asymmetry. The commercial plates used during bilateral sagittal split osteotomy (BSSO) surgery are often not tailored to individual patients and may lack sufficient fixation stability, increasing the risk of mandibular relapse. This study proposes a patient-specific plate design by collecting CT images of 30 cases of hemifacial microsomia to statistically analyze mandibular asymmetry.Methods: The design process integrates topology and parameter optimization analysis to develop the plate (TOPO plate), aiming for a lightweight structure with enhanced fixation stability. The structural strength and fixation stability of the TOPO plate were verified through static and dynamic four-point bending tests, as well as biomechanical testing, ensuring compliance with clinical requirements and regulatory approval for market release.Results: The TOPO plate features an asymmetrical design tailored to patient’s specific anatomy. In static/dynamic four-point bending tests, the structural strength of the TOPO plate exceeded that of commercial plates, with average proof loads of 326.9N for the right side and 389.85N for the left side. Biomechanical analysis and testing confirmed that the TOPO plate effectively limits the displacement of the mandibular segment (average 0.45mm), providing favorable fixation stability and thereby reducing the risk of relapse.Discussion: In summary, the TOPO plate is applicable for most patients with hemifacial microsomia, meeting the biomechanical requirements of the mandible and complying with market conditions. This patient-specific approach promises improved outcomes in mandibular fixation stability. |
| 關鍵字 | ASTM F382; BSSO; hemifacial microsomia; parameter optimization; patient-specific implant; relapse; topology optimization. |
| 語言 | en |
| ISSN | 2296-4185 |
| 期刊性質 | 國外 |
| 收錄於 | SCI |
| 產學合作 | |
| 通訊作者 | |
| 審稿制度 | 否 |
| 國別 | CHE |
| 公開徵稿 | |
| 出版型式 | ,電子版 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/129436 ) |