期刊論文
| 學年 | 112 |
|---|---|
| 學期 | 1 |
| 出版（發表）日期 | 2023-08-04 |
| 作品名稱 | Design, synthesis, and evaluation of 1,2,3-triazole-based benzenesulfonamide and flavonol hybrid molecules as anticancer agents |
| 作品名稱（其他語言） | |
| 著者 | Shih, Tzenge-lien |
| 單位 | |
| 出版者 | |
| 著錄名稱、卷期、頁數 | Journal of the Chinese Chemical Society 70(10), p.1924-1936 |
| 摘要 | Background The design and synthesis of hybrid molecules will explore finding new drugs. Objectives The synthesized hybrid molecules to evaluate their biological properties. Methods Apply click chemistry to tether flavonols and benzenesulfonamide. Results Two drug candidates show potential against lung cancer. Conclusions Two drug candidates did not affect the normal cells and provided a new drug design route. |
| 關鍵字 | 1,2,3-triazole;benzenesulfonamide;click chemistry;flavonol;human non-small-cell lung cancer cells;hybrid molecules |
| 語言 | en_US |
| ISSN | |
| 期刊性質 | 國內 |
| 收錄於 | SCI |
| 產學合作 | |
| 通訊作者 | Tzenge-Lien SHih |
| 審稿制度 | 是 |
| 國別 | TWN |
| 公開徵稿 | |
| 出版型式 | ,電子版 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/124672 ) |