期刊論文
| 學年 | 110 |
|---|---|
| 學期 | 2 |
| 出版（發表）日期 | 2022-04-01 |
| 作品名稱 | Rapid Identification of Commercial Frankincense Products by MALDI-TOF Mass Spectrometry |
| 作品名稱（其他語言） | |
| 著者 | Shang-Chih Lai; Ren-In You; Tz-Ting Chen; Yu Chang; Chao-Zong Liu; Hao-Ping Chen; Chunhung Wu |
| 單位 | |
| 出版者 | |
| 著錄名稱、卷期、頁數 | Combinatorial Chemistry & High Throughput Screening 25(5), p.895-905 |
| 摘要 | Background: Frankincense is a resin secreted by the Boswellia tree. It is used in perfumery, aromatherapy, skincare, and traditional Chinese medicine. However, all Boswellia species are under threat owing to habitat loss and overexploitation. As a result, the market is getting flooded with counterfeit frankincense products. Objective: This study aims to establish a high-throughput method to screen and identify the authenticity of commercial frankincense products. We report, for the first time, a matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS)-based method for rapid and high-throughput screening of frankincense samples. Methods: MALDI-TOF MS, HPLC, thin-layer chromatography (TLC), and in vitro antiinflammatory activity assay were used to examine the frankincense samples. Results: Well-resolved peaks of frankincense triterpenoids in the spectra were observed in the crude extract of commercial samples, including α-boswellic acids (αBAs), β-boswellic acids (βBAs), 11-keto-β-boswellic acids (KBAs), acetyl-11-keto-β-boswellic acids (AKBAs), and their esters. These compounds can be used as indicators for determining the authenticity of frankincense. Conclusion: Unlike LC–MS, which is a time-consuming and expensive method, and TLC, which requires a reference sample, our inexpensive, rapid high-throughput identification method based on MALDI-TOF MS is ideal for large-scale screening of frankincense samples sold in the market. |
| 關鍵字 | Acetyl-11-keto-β-boswellic acid;anti-inflammatory;frankincense;HPLC;MALDI-TOF MS;IUCN |
| 語言 | en |
| ISSN | 1875-5402; 1386-2073 |
| 期刊性質 | 國外 |
| 收錄於 | SCI |
| 產學合作 | |
| 通訊作者 | Chunhung Wu |
| 審稿制度 | 是 |
| 國別 | ARE |
| 公開徵稿 | |
| 出版型式 | ,電子版,紙本 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/123407 ) |