期刊論文
| 學年 | 103 |
|---|---|
| 學期 | 1 |
| 出版（發表）日期 | 2014-09-01 |
| 作品名稱 | Dynamic Structural Transformation of Resveratrol-Modified Stearate Liposomes Led to a Spontaneous Drug Release System |
| 作品名稱（其他語言） | |
| 著者 | Chen, Li-Chou; Lin, Shih-Shan; Li, Cun-Zhao; Hsu, Hsiu-Fu; Weng, Yu-Jong; Cheng, Chien-Chung |
| 單位 | 淡江大學化學學系 |
| 出版者 | Oxford: Wiley-Blackwell Publishing Ltd. |
| 著錄名稱、卷期、頁數 | Journal of the Chinese Chemical Society 60(9), pp.1099-1102 |
| 摘要 | A mono-substituted resveratrol derivative, resveratrol-modified stearate (RMS), was synthesized by selectively coupling of stearic acid to the monohroxyphenyl of resveratrol in order to enhance both the stability and bioavailability of resveratrol. The RMS self-assembles into liposomes and a series of suprastructural transformations into metastable helical ribbon, linear wire-like structures, and inert spherical nanoparticles were detected that may be induced by the hydrogen-bonding interactions. As a model for drug-release investigations, gold nanoparticles (AuNPs) were encapsulated successfully by RMS to generate vesicles and succeed to release AuNPs druing the transformation to a ribbon-like metastable stucture at ambient temperature. |
| 關鍵字 | Liposome; Resveratrol; Stearate; Helical transformation; Drug-release |
| 語言 | en_US |
| ISSN | 2192-6549 |
| 期刊性質 | |
| 收錄於 | SCI |
| 產學合作 | |
| 通訊作者 | |
| 審稿制度 | 是 |
| 國別 | GBR |
| 公開徵稿 | |
| 出版型式 | 電子版 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/98510 ) |