期刊論文
| 學年 | 84 |
|---|---|
| 學期 | 1 |
| 出版（發表）日期 | 1995-08-01 |
| 作品名稱 | Human aldehyde dehydrogenase E3 isozyme is a betaine aldehyde dehydrogenase |
| 作品名稱（其他語言） | |
| 著者 | Chern, Ming-kai; Pietruszko, Regina |
| 單位 | 淡江大學生命科學研究所 |
| 出版者 | Maryland Heights: Academic Press |
| 著錄名稱、卷期、頁數 | Biochemical and Biophysical Research Communications 213(2), pp.561-568 |
| 摘要 | The E3 isozyme of human aldehyde dehydrogenase (EC 1.2.1.3), with broad substrate specificity, which also catalyzes dehydrogenation of 4-aminobutyraldehyde, was purified and sequenced recently (1,3). It has been shown during this investigation to have betaine aldehyde dehydrogenase activity. Betaine aldehyde and 4-aminobutyraldehyde activities copurified on six chromatographic columns. Molecular properties of the homogeneous product were identical with those of E3 isozyme. Activity with betaine aldehyde was considerably higher than that with 4-aminobutyraldehyde, the best known substrate. Thus, human E3 isozyme and betaine aldehyde dehydrogenase (EC 1.2.1.8) are the same enzyme. |
| 關鍵字 | |
| 語言 | en |
| ISSN | 0006-291X |
| 期刊性質 | 國外 |
| 收錄於 | |
| 產學合作 | |
| 通訊作者 | Pietruszko, Regina |
| 審稿制度 | |
| 國別 | USA |
| 公開徵稿 | |
| 出版型式 | 紙本 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/61855 ) |