期刊論文
| 學年 | 101 |
|---|---|
| 學期 | 2 |
| 出版（發表）日期 | 2013-02-18 |
| 作品名稱 | The First Synthesis of 7-(Hydroxymethyl)thiepane-3,4,5-triols from D-(-)-Quinic Acid |
| 作品名稱（其他語言） | |
| 著者 | Shih, Tzenge-Lien; Gao, Wei-Lin |
| 單位 | 淡江大學化學學系 |
| 出版者 | Kidlington: Pergamon |
| 著錄名稱、卷期、頁數 | Tetrahedron 69(7), pp.1897-1903 |
| 摘要 | Seven thiepanes, the seven-membered-ring thiosugars, were first synthesized in 11–12 steps starting from d-(−)-quinic acid. Each thiepane is unique for its flexible conformation with a hydroxymethyl group at its C7 position. The key step was the deprotection of ether groups in compounds 7, 8, and 18–21 by 1.0 M BCl3 of CH2Cl2 solution at −78 °C to lead to the corresponding thiepanes. These target molecules all exhibited the twisted chair conformation that fully agreed with our previous report. |
| 關鍵字 | Glycosidase inhibitors; d-(−)-Quinic acid; Thiepanes; Thiosugars |
| 語言 | en_US |
| ISSN | 0040-4020 |
| 期刊性質 | 國外 |
| 收錄於 | SCI |
| 產學合作 | |
| 通訊作者 | Shih, Tzenge-Lien |
| 審稿制度 | 是 |
| 國別 | GBR |
| 公開徵稿 | |
| 出版型式 | ,紙本 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/89040 ) |