期刊論文
| 學年 | 95 |
|---|---|
| 學期 | 1 |
| 出版（發表）日期 | 2007-01-01 |
| 作品名稱 | Electrochemical Detection of High-Sensitivity C-Reactive Protein Based on Biomimic Design of Electroactive Nanoassembly Multilayers |
| 作品名稱（其他語言） | |
| 著者 | 李世元; Chien, Ling-chih; Chiu, Nan-fu; Yang, Lung-jieh; Yao-jo |
| 單位 | 淡江大學化學學系 |
| 出版者 | |
| 著錄名稱、卷期、頁數 | Journal of Bionanoscience1, pp.44-50 |
| 摘要 | In this study, the gold electrode was modified with a ferrocene-terminated alkanethiol and phospholipid complex layer, which is designed and fabricated to serve as a C-reactive protein sensor using electrochemical determination. The scope of this research is to know whether a ferrocene-terminated self-assembled monolayer and hydrogenated phosphocholine hybrid bilayer could be used to perform C-reactive protein detection or not. After a series of experiments, the result shows that mixed electroactive SAM can facilitate electrons transferring from the solution to the electrode. And after coating phospholipids, this phenomenon seems to be hindered from the electrode. But this provoked small electrical signal of the recognition layer still allows for further usage. According to the result, it can be used to measure C-reactive protein and its electrochemical property and the changes of the electrode's electron transfer ability are characterized by cyclic voltammetry. This study demonstrates self-assembled ferrocene-terminated alkanethiol and phospholipid complex structure has potential as a C-reactive protein sensor and is stable to detect in the aqueous phase. |
| 關鍵字 | BIOSENSOR;C-REACTIVE PROTEIN;CYCLIC VOLTAMMETRY;FERROCENE-TERMINATED ALKANETHIOL;PHOSPHOLIPID;SELF-ASSEMBLED MONOLAYER |
| 語言 | en |
| ISSN | |
| 期刊性質 | 國內 |
| 收錄於 | |
| 產學合作 | |
| 通訊作者 | |
| 審稿制度 | 否 |
| 國別 | TWN |
| 公開徵稿 | |
| 出版型式 | ,電子版 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/61580 ) |