期刊論文
| 學年 | 79 |
|---|---|
| 學期 | 1 |
| 出版（發表）日期 | 1990-08-23 |
| 作品名稱 | A comparison of the parameter estimating procedures for the michaelis-menten model |
| 作品名稱（其他語言） | |
| 著者 | Tseng, Shio-jenn; Hus, Jyh-ping |
| 單位 | 淡江大學數學學系 |
| 出版者 | London: Academic Press |
| 著錄名稱、卷期、頁數 | Journal of Theoretical Biology 145(4), pp.457-464 |
| 摘要 | The performance of four parameter estimating procedures for the estimation of the adjustable parameters in the Michaelis-Menten model, the maximum initial rate Vmax, and the Michaelis-Menten constant Km, including Lineweaver & Burk transformation (L-B), Eadie & Hofstee transformation (E-H), Eisenthal & Cornish-Bowden transformation (ECB), and Hsu & Tseng random search (H-T) is compared. The analysis of the simulated data reveals the followings: (i) Vmax can be estimated more precisely than Km. (ii) the sum of square errors, from the smallest to the largest, follows the sequence H-T, E-H, ECB, L-B. (iii) Considering the sum of square errors, relative error, and computing time, the overall performance follows the sequence H-T, L-B, E-H, ECB, from the best to the worst. (iv) The performance of E-H and ECB are on the same level. (v) L-B and E-H are appropriate for pricesly measured data. H-T should be adopted for data whose error level are high. (vi) Increasing the number of data points has a positive effect on the performance of H-T, and a negative effect on the performance of L-B, E-H, and ECB. |
| 關鍵字 | |
| 語言 | en |
| ISSN | 0022-5193 1095-8541 |
| 期刊性質 | 國外 |
| 收錄於 | |
| 產學合作 | |
| 通訊作者 | |
| 審稿制度 | |
| 國別 | GBR |
| 公開徵稿 | |
| 出版型式 | 紙本 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/41358 ) |