期刊論文

學年 91
學期 2
出版(發表)日期 2003-04-01
作品名稱 Electrophoresis of biological cells:charge-regulation and multivalent counterions association model
作品名稱(其他語言)
著者 Hsu, Jyh-ping; Hseih, T. S.; Young, T. H.; 曾琇瑱; Tseng, Shio-jenn
單位 淡江大學數學學系
出版者 Wiley-Blackwell
著錄名稱、卷期、頁數 Electrophoresis 24(9), pp.1338-1346
摘要 The electrophoresis of a biological cell is analyzed theoretically. An entity, which is of amphoteric nature, is used to simulate its electrophoretic behavior. To reflect conditions of practical interest, we assume that the liquid phase contains mixed (a:b)+(c:b) electrolytes, where a and c are the valences of cations, and b is the valence of anions. We consider the case where the surface of a cell contains both bivalent acidic and monovalent basic functional groups, the dissociation/association of them yields fixed surface charge, and the multivalent cations in the liquid phase are allowed to combine with dissociated acidic functional groups, which has the effect of lowering the charge density on cell surface. The electrophoretic behaviors of a cell under various conditions are illustrated. The results obtained can be used to identify the types of functional groups that may be present on cell surface. On the other hand, if the surface functional groups involved in cell electrophoresis are known, then their density and the associated dissociation/association constants can be estimated from experimental data.
關鍵字
語言 en
ISSN 0173-0835
期刊性質 國內
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國別 TWN
公開徵稿
出版型式 ,電子版
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