關鍵字查詢 | 類別:會議論文 | | 關鍵字:Liquid Crystal-based Immunoassay for Detecting Human Serum Albumin

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序號 學年期 教師動態
1 102/1 化學系 陳志欣 教授 會議論文 發佈 Liquid Crystal-based Immunoassay for Detecting Human Serum Albumin , [102-1] :Liquid Crystal-based Immunoassay for Detecting Human Serum Albumin會議論文Liquid Crystal-based Immunoassay for Detecting Human Serum Albumin陳志欣; 何文薰淡江大學化學學系Liquid Crystal-based ImmunoassaySpringerThe first OPU–TKU International Symposium on Frontier Chemistry and Materials for the 21st CenturyHuman serum albumin (HSA) is the most abundant protein in human blood plasma. It is commonly used as a biomarker in urine samples to identify the chronic kidney disease (CKD) caused by high blood pressure or diabetes. In our research, a thin layer of liquid crystals (LCs) is used as a readout system for developing an immunoassay that reports the presence of HSA in the aqueous solution with optical signals. The detection principle of this assay is based on the variation of surface density of protein upon the specific binding of HSA on anti-HSA immobilized surface, which leads a dark-to-bright transition of LC images under cross polarizers. Our results show that the LC-based immunoassay can detect HSA at
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