關鍵字查詢 | 類別:研究報告 | | 關鍵字:電腦模擬計算在腫瘤中大分子藥物的擴散係數

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序號 學年期 教師動態
1 99/1 資創系 黃煌文 副教授 研究報告 發佈 電腦模擬計算在腫瘤中大分子藥物的擴散係數 , [99-1] :電腦模擬計算在腫瘤中大分子藥物的擴散係數研究報告 電腦模擬計算在腫瘤中大分子藥物的擴散係數黃煌文資訊創新與科技學系行政院國家科學委員會補助專題研究計畫行政院國家科學委員會補助專題研究計畫To be one of effective delivery of anticancer therapeutic agents must rely on macromolecular drug carriers because they appear to target tumors and have limited toxicity in normal tissue. However, solid tumors consist of extreme complicated structures: a porous interstitium and a poorly organized vasculature composed of a network of capillaries with highly permeable walls. As anticancer drugs distribute within tumors, they form gradients from tumour blood vessels that change with time as the drug is cleared from the body. The purpose of this study is to better understand macromolecular drug transport mechanisms within solid tumors by numerical calculation. With integrating experimental information on dextran covalently li
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