關鍵字查詢 | 類別:期刊論文 | | 關鍵字:Production of potent antidiabetic compounds from shrimp head powder via Paenibacillus conversion

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序號 學年期 教師動態
1 107/1 化學系 王三郎 教授 期刊論文 發佈 Production of potent antidiabetic compounds from shrimp head powder via Paenibacillus conversion , [107-1] :Production of potent antidiabetic compounds from shrimp head powder via Paenibacillus conversion期刊論文Production of potent antidiabetic compounds from shrimp head powder via Paenibacillus conversionVan Bon Nguyen; San-Lang WangShrimp heads;Marine processing;Antidiabetes;Paenibacillus;Nicotinic acid, AdenineProcess Biochemistry 76, p.18-24Natural α-glucosidase inhibitors (aGIs) are of great interest as an efficacious and safe therapy for type 2 diabetes, which is an ongoing global health issue. The aim of this study is to utilize shrimp head powder (SHP), an abundant and low-cost material, for the biosynthesis, isolation, and identification of active antidiabetic compounds. SHP was efficiently converted to aGIs via Paenibacillus sp. TKU042 fermentation. Fermented SHP (fSHP) by this strain possesses high pH stability, and stronger yeast α-glucosidase inhibitory activity (92%) than that of acarbose (60%). aGI productivity increased more than 2-fold after optimization (from 225 U/mL to 560
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