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數學系 温啟仲 教授於
期刊論文
發佈
Flavone is efficient to protect zebrafish fins from UV-induced damage
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[100-2]
:Flavone is efficient to protect zebrafish fins from UV-induced damage期刊論文Flavone is efficient to protect zebrafish fins from UV-induced damageTsai, I.T.; Yang, Z.S.; Lin, Z.Y.; Wen, C.C.; Cheng, C.C.; Chen, Y.H.淡江大學數學學系暨研究所New York: Informa HealthcareDrug and Chemical Toxicology 35(3), pp.341-46We used ultraviolet (UV)-induced fin damage in zebrafish as a system for evaluating the chemopreventive potential of flavonoids. Chemopreventive effects of each compound, including flavone, flavanone, and chalcone, on fin development were evaluated using Kaplan-Meier analysis and Cox proportional hazards regression. Results showed that 1) flavone has the highest capacity to protect zebrafish fins from UV-induced damages among other groups; 2) zebrafish fins in the UV+1 ppm flavone group are 1.02~9.60 times more likely to return to normal fins than ones in the UV-only group, but fins in the UV+20 ppm flavone group are only 0.45~5.66 times more likely to recover; and 3) flavone significantly reduc
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化學系 陳曜鴻 教授於
期刊論文
發佈
Flavone is efficient to protect zebrafish fins from UV-induced damages
,
[100-2]
:Flavone is efficient to protect zebrafish fins from UV-induced damages期刊論文Flavone is efficient to protect zebrafish fins from UV-induced damagesTsai, I-Ting; Yang, Zhi-Shiang; Lin, Zi-Yu; Wen, Chi-Chung; Cheng, Chien-Chung; Chen, Yau-Hung淡江大學數學學系; 淡江大學化學學系Chalcone; fin; flavone; UV; zebrafishDrug and Chemical Toxicology 35(3), pp.341-346.We used ultraviolet (UV)-induced fin damage in zebrafish as a system for evaluating the chemopreventive potential of flavonoids. Chemopreventive effects of each compound, including flavone, flavanone, and chalcone, on fin development were evaluated using Kaplan-Meier analysis and Cox proportional hazards regression. Results showed that 1) flavone has the highest capacity to protect zebrafish fins from UV-induced damages among other groups; 2) zebrafish fins in the UV+1 ppm flavone group are 1.02~9.60 times more likely to return to normal fins than ones in the UV-only group, but fins in the UV+20 ppm flavone group are only 0.45~5.66 times more likely to
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