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序號 學年期 教師動態
1 106/2 資傳系 卓美玲 副教授 期刊論文 發佈 色手止步--談色情假新聞置入行銷管制 , [106-2] 摘要:
2 107/1 中文系 楊宗翰 助理教授 期刊論文 發佈 世代作為方法——關於《台灣一九七○世代詩人詩選集》 , [107-1] 摘要:
3 107/1 資工系 林其誼 副教授 期刊論文 發佈 An Experimental System for MQTT/CoAP-based IoT Applications in IPv6 over Bluetooth Low Energy , [107-1] 摘要:With the rapid development of Internet of Things (IoT), it is an inevitable trend that all things will get connected to the Internet to form various intelligent services such as Industry 4.0, smart home, smart medical care, etc. To make such intelligent IoT services practicable, it is vital to have a low-power link-layer technology that can accommodate a diversity of upper-layer networking protocols. Currently, there are many popular low-power wireless networking technologies for IoT such as ZigBee and Bluetooth Low Energy (BLE). Because of the ubiquity of BLE-enabled smartphones nowadays, BLE has gained much attention in the IoT industry recently. In this research, we aim at implementing an IPv6 over BLE experimental system using Raspberry Pi 3 and nRF51-DK development boards, and then run the Message Queuing Telemetry Transport for Sensor Networks (MQTT-SN) protocol and the Constrained Application Protocol (CoAP) over the protocol stack of IPv6/BLE. Specifically, in our experimental system every BLE node is IPv6-addressable and accessible through the MQTT/CoAP protocols from anywhere over the Internet. Moreover, to ease user accesses from ordinary web browsers, we build two gateways as the web servers for end users, which receive real-time sensor data via CoAP or MQTT-SN protocols and then push the data to end users' browsers. The gateways are also designed to routinely request sensor data and then forward the data to cloud database platforms, which serve as the data sources for historical sensor data. Preliminary results showed that our system is capable of achieving the designed goals and is user-friendly. Compared with the non-IP based BLE sensor networks, our implementation can be integrated into a variety of existing and widely used IP-based applications easily.
4 107/1 化學系 王三郎 教授 期刊論文 發佈 Isolation and identification of potent antidiabetic compounds from Antrodia cinnamomea - An edible Taiwanese mushroom , [107-1] 摘要:Antrodia cinnamomea (AC), an edible Taiwanese mushroom, has been recognized as a valuable natural resource with vast biological and medicinal benefits. Recently, the hypoglycemic and anti-diabetic effects of AC were mentioned in several studies. However, no studies have investigated α-glucosidase inhibitors from AC fruiting bodies (ACFB) as they relate to type 2 diabetes (T2D) treatment. The purpose of this study was to gain evidence of potent α-glucosidase inhibitory effects, as well as isolate, identify and characterize the active compounds of ACFB. The MeOH extract of ACFB demonstrated potent α-glucosidase inhibitory activity, and possessed high pH stability (pH 2–11) and thermostable properties at 40–50 ◦C. Further purification led to the isolation of eight constituents from ACFB, identified as: 25S-antcin K (1), 25R-antcin K (2), dehydrosulphurenic acid (3), 25S-antcin I (4), 25S-antcin B (5), 25R-antcin B (6), dehydroeburicoic acid (7) and eburicoic acid (8). Notably, the ACFB extract and its identified compounds, except 1, 4, and 6 demonstrated a greater effect (EC50 = 0.025–0.21 mg/mL) than acarbose (EC50 = 0.278 mg/mL). As such, these active compounds were determined to be new potent mushroom α-glucosidase inhibitors. These active compounds were also identified on the HPLC fingerprints of ACFB.
5 107/1 化學系 王三郎 教授 期刊論文 發佈 Reclamation of marine chitinous materials for chitinase and protease production via microbial conversion by Paenibacillus macerans , [107-1] 摘要:: Chitinous materials from marine byproducts elicit great interest among biotechnologists for their potential biomedical or agricultural applications. In this study, four kinds of marine chitinous materials (squid pens, shrimp heads, demineralized shrimp shells, and demineralized crab shells) were used to screen the best source for producing chitosanase by Paenibacillus macerans TKU029. Among them, the chitosanase activity was found to be highest in the culture using the medium containing squid pens as the sole carbon/nitrogen (C/N) source. A chitosanase which showed molecular weights at 63 kDa was isolated from P. macerans cultured on a squid pens medium. The purified TKU029 chitosanase exhibited optimum activity at 60 ◦C and pH 7, and was stable at temperatures under 50 ◦C and pH 3-8. An analysis by MALDI-TOF MS revealed that the chitosan oligosaccharides (COS) obtained from the hydrolysis of water-soluble chitosan by TKU029 crude enzyme showed various degrees of polymerization (DP), varying from 3–6. The obtained COS enhanced the growth of four lactic acid bacteria strains but exhibited no effect on the growth of E. coli. By specialized growth enhancing effects, the COS produced from hydrolyzing water soluble chitosan with TKU029 chitinolytic enzymes could have potential for use in medicine or nutraceuticals.
6 107/1 教科系 顧大維 教授 期刊論文 發佈 應用合作學習影響高職學生數學學習成就之行動研究 , [107-1] 摘要:近年來,由於技職學院、科技大學蓬勃發展,升學管道亦更加多元,高職學生多數仍然選擇的是繼續升學。不過,學生對於基礎學科的能力培養較為不足,學習上亦缺乏自我學習能力。因此,自研究者任教高職多年以來,一直重複使用相同的傳統式教學方法,深信只要教師秉持著認真負責的態度教育學生、傳授知識給學生,學生一定會有所感覺,必以相同的態度回報老師。但是,幾年下來,研究者發現,高職學生的程度一年不如一年,對於數學的學習更是越來越沒有自信,甚至多數學生找不到學習目標,更嚴重的情況甚至是放棄數學。 因此,在面對自我教學的瓶頸之下,研究者利用設計分組學習教材、小組合作學習、小組競賽及個別小考方式,配合學生學習期間的反饋及觀察、與學生晤談及教師自我省思,改變自我的教學方法,在課堂上階段性的採行「合作學習」的教學方式,對所任教的高職學生進行行動研究,進而讓學生重拾學習數學的信心,以統計方法成對樣本比對分析,驗證確實提升了學生的學習成就。 研究者以個人任教背景條件,採用合作學習創造學生自我學習機會、改變學生數學學習成就,利用上述提及教學方法之改變,創造團隊合作學習機會,以此研究結果,相信可以提供未來應用於其他教學領域環境上。
7 102/1 水環系 吳昀達 助理教授 期刊論文 發佈 Propagation of solitary waves over a submerged permeable breakwater , [102-1] 摘要:
8 102/2 水環系 吳昀達 助理教授 期刊論文 發佈 Three-dimensional numerical simulation on the interaction of solitary waves and porous breakwaters , [102-2] 摘要:
9 106/1 水環系 吳昀達 助理教授 期刊論文 發佈 Propagation of solitary waves over double submerged barriers , [106-1] 摘要:Protection of nearshore area by means of artificial structure is an important issue for coastal engineering community. In this study, we aim to investigate wave hydrodynamics and hydrodynamic performance due to solitary waves interacting with double submerged barriers. Double barriers, put bottom-mounted vertically on the flat seafloor and also paralleled to each other, are considered as a wave absorber. New experiments are carried out to provide measured data for model validation. Numerical simulations are performed using a depth- and phase-resolving model, based on the Reynolds-Averaged Navier–Stokes equations with a non-linear k- ɛ turbulence closure model. Model–data comparisons show good agreements in terms of free surface fluctuations in time histories and error analyses are performed. Numerical results are then used to study the variations of the free surface motions of breaking waves and the flow fields. In particular, the model results reveal that the optimal horizontal distance, judged as minimum wave transmission, between two submerged barriers is approximately 2.5 times the still water depth for present wave conditions and obstacle geometries. Furthermore, numerical model is extended to evaluate the functional efficiency of a dual-slotted-barrier system with different obstacle configurations under various conditions of solitary waves by means of energy reflection, transmission and dissipation coefficients.
10 107/1 教政所 張鈿富 教授 期刊論文 發佈 Estimating the Gaps between Potential Enrollment Numbers and Kindergarten Capacities by Using Time Series Models , [107-1] 摘要:This study selected Taiwan as a target to tackle the issue of gap between potential enrollment numbers and kindergarten capacities (KC). The purposes of this study are to realize the effect of 0-year babies (ZYB) declining existing in Taiwan, to project the future development of ZYB and to estimate the gap between ZYB and KC in the system. This study selects the ARIMA model to verify the robustness of forecasting ZYB. Employing the projecting data of ZYB, this study calculates the gaps between ZYB and estimated KC in next decade. Based on the fittest ARIMA model and the gap estimation, this study found the one-year model of KC is oversupply and the gaps will increase steadily. The gaps between demands and supplies in two-year model of KC are diminishing in next decade. This study provides a practical method to detect whether it is an issue of oversupply in the kindergarten system. Both predict and estimate models provide useful knowledge to reinvent management strategies to ameliorate the issue of the system.
11 107/1 教政所 張鈿富 教授 期刊論文 發佈 A Study on the Relationship Among Interpersonal Network, Self-Regulation Learning Strategies and Learning Performance of New Immigrant Students , [107-1] 摘要:This study investigated the difference of interpersonal network, self-regulation learning strategies, and learning performance between new immigrant and non-immigrant students in junior high schools as well as the relationship among the three variables by using the data from the database of Taiwan Assessment of Student Achievement. This study sampled 610 questionnaires from new immigrant students that 7,744 questionnaires from non-immigrant students. The structure of factors for each variable was determined through factor analysis, and multivariate analysis of variance and structural equation modeling were subsequently conducted. This study found that new immigrant students, compared with non-immigrant students, had inferior information processing, cognitive regulation, and connection strategies in terms of self-regulation learning strategies, weaker family relations and peer relationships regarding their interpersonal network, and lower individual and group learning performance. Moreover, new immigrant students’ interpersonal network and self-regulation learning strategies both had critical influence on learning performance, and interpersonal network had an indirect effect on learning performance through self-regulation learning strategies. The findings can serve as a reference for the authorities to improve related strategies to increase the learning effect for the specific student group.
12 107/1 化材系 何啟東 教授 期刊論文 發佈 Multi-objective Optimization of Mixed Membrane Reactors for Autothermal Reforming of Methane , [107-1] 摘要:
13 106/2 化材系 何啟東 教授 期刊論文 發佈 Mechanistic kinetic models describing impact of early attachment between Chlorella vulgaris and polyurethane foam material in fluidized bed bioreactor on lipid for biodiesel production , [106-2] 摘要:
14 106/2 會計系 方郁惠 副教授 期刊論文 發佈 An App a Day Keeps a Customer Connected: Explicating Brand Loyalty through the Lens of Affordance and Service-dominant Logic , [106-2] 摘要:
15 102/2 數位資訊組 傅淑琴 編纂 期刊論文 發佈 Shopping in Cyberspace: Adolescent Technology Acceptance Attitude with Decision-making Styles , [102-2] 摘要:Researchers have explored adolescents' online buying habits as the internet has developed and teenagers' incomes have increased. In this study, that tries to understand adolescent buying behavior, and adolescent decision-making styles as input variable and online shopping behavior as output variable. The Technology Acceptance Model (TAM) is included as a moderating variable. A total of 1,614 adolescents aged 16 to 30 in Taiwan were participants. Correlation, regression, and covariance analyses were used. Results show a positive correlation between adolescents' consumer decision-making styles and purchasing behavior (including planned and unplanned purchases). In addition, compulsive purchases under unplanned purchases showed a positive moderating effect. Recognition of ease of use in TAM had a positive moderating effect on compulsive purchases categorized under unplanned purchases. This research examined the moderating effect of variables in TAM, verifying their effects.
16 107/1 電機系 丘建青 教授 期刊論文 發佈 Comparison of SIRM and SOM on Microwave Imaging of the Rough Surface , [107-1] 摘要:
17 104/2 公行系 詹立煒 助理教授 期刊論文 發佈 從都市論探討影響臺灣都市政府決策作成的因子 , [104-2] 摘要:因政策決定了政治,而所有的政治都是地方性。所以都市政治及其對政治選擇的影響,為本研究所要探討主要問題。對此,本文採用文獻回顧的方式,彙整國內外針對都市政治和地方財政的相關理論及文獻,分從政治、經濟和政治經濟三個面向探討其觀點和合適性的問題,以及三種政策類型其異同和影響。並且檢視我國目前都市的制度結構和財政情況,然後彙整出影響我國都市政府政策抉擇的可能因素。
18 103/2 公行系 詹立煒 助理教授 期刊論文 發佈 臺灣國會制度中的遊說操控-地方制度法第四條「準用直轄市」修正案歷程剖析 , [103-2] 摘要:因為政治參與者都有想贏的動機,所以W. Riker認為參與者利用集體決策的博弈過程,採取「遊說操控」以獲得想要的結果。本研究假定歷經三屆委員提案的地制法第四條準用案,能夠在第六屆立法院三讀通過,係因參與者運用上述策略而成功。對此,本文將地制法第四條準用案能否通過界定為結果變項,遊說操控的三項要素為因果變項,時序政治事件和既有制度為強化因果關係的前例變項。同時透過因果程序追蹤的方式,以第四、五、六屆立委的16項提案做為小樣本個案實例,梳理其敘事脈絡,以敘述統計歸納提案類別,並藉由賽局理論的政策空間模型解析參與者的策略互動。然後針對三項問題進行推論分析:委員會召委對本案具有何種影響?提案委員是否採取策略投票?朝野如何進行議題面向操縱以改變集體決策結果?研究發現,委員會召委對於議題支配具有明顯影響力,並反映在議程、審查和協商的過程之中。其次,提案委員考量選區和可行性高低而採取策略投票並組建最小勝利聯盟。第三,黨團協商提供議題面向操縱的機會,使有意發動的參與者能夠以否決者之角色和利用獲利轉換的方式以影響院會決策。綜上,透過上述方法分析所得的結果,呈現出本文具有靜態法制分析與動態決策研究之特性。
19 106/2 戰略所 王高成 教授 期刊論文 發佈 冷戰後美國國家安全戰略之演變與影響 , [106-2] 摘要:
20 107/1 電機系 翁慶昌 教授 期刊論文 發佈 Visual object recognition and pose estimation based on a deep semantic segmentation network , [107-1] 摘要:
21 105/2 公行系 詹立煒 助理教授 期刊論文 發佈 兩岸經濟類協議交付立法院審議方式之分析 , [105-2] 摘要:2010年第7屆立法院審議兩岸經合協議 (ECFA),在國民黨席次優勢下院會完成批准程序。2014年第8屆立法院審議兩岸服貿協議的過程中,因協議內容和議事程序的問題而引發佔領國會的事件。服貿協議屬經合協議後續之一部分,但為何國民黨無法在掌握國會席次優勢的會期通過。從事件的結果、理論觀點和實務運作而言,性質相同的議案、且屬一致政府的關係下,卻有不同的審議方式,此間差異即有值得探討之處。本文從理性選擇制度論的角度探討立法組織和程序對議案審議的影響,研究方法採個案研究之方式,檢視立法院相關法規、公報、議事錄和新聞報導資料。並從反事實的角度針對所要探討的問題予以推論並分析:第一,立法院如何審議我國對外簽署的經濟類協議;第二,立法院多數黨如何運用議事規範影響議案審議的程序;第三,立法院多數黨如何施展議程設定和議價協商的策略;第四,立法院多數黨與行政部門對於兩岸經濟類協議的審議方式是否一致。從個案分析結果發現,立法院過去審議我國對外的7個經濟類協議,院會依照議事先例採全案表決;其次,兩岸經濟類協議的審議方式並非一致,兩岸經合協議與智財協議則是以逕付二讀的方式通過,但在審議服貿協議時,國民黨在黨團協商為了換取民進黨在12年國教法案的同意而對逐條審查的主張讓步,民進黨藉由委員會召委議程設定的權力召開16場公聽會,藉以延後服貿協議的審查時間;最後,第8屆國民黨之所以未能以國會多數黨優勢通過議案,從立法院公報紀錄發現,區域立委面對具爭議性的服貿協議和連任壓力之下而不得不調整其議事策略,而且委員彼此立場也不一致,嗣後318公民運動的發生,使得服貿協議最終未能在立法院第8屆完成審議。
22 105/1 化學系 蔡旻燁 助理教授 期刊論文 發佈 Molecular Mechanism of Facilitated Dissociation of Fis Protein from DNA , [105-1] 摘要:Fis protein is a nucleoid-associated protein that plays many roles in transcriptional regulation and DNA site-specific recombination. In contrast to the naïve expectation based on stoichiometry, recent single-molecule studies have shown that the dissociation of Fis protein from DNA is accelerated by increasing the concentration of the Fis protein. Because the detailed molecular mechanism of facilitated dissociation is still not clear, in this study, we employ computational methods to explore the binding landscapes of Fis:DNA complexes with various stoichiometries. When two Fis molecules are present, simulations uncover a ternary complex, where the originally bound Fis protein is partially dissociated from DNA. The simulations support a three-state sequential kinetic model (N ⇄ I → D) for facilitated dissociation, thus explaining the concentration-dependent dissociation.
23 106/1 化學系 蔡旻燁 助理教授 期刊論文 發佈 Comparing the Aggregation Free Energy Landscapes of Amyloid Beta(1–42) and Amyloid Beta(1–40) , [106-1] 摘要:Using a predictive coarse-grained protein force field, we compute and compare the free energy landscapes and relative stabilities of amyloid-β protein (1–42) and amyloid-β protein (1–40) in their monomeric and oligomeric forms up to the octamer. At the same concentration, the aggregation free energy profile of Aβ42 is more downhill, with a computed solubility that is about 10 times smaller than that of Aβ40. At a concentration of 40 μM, the clear free energy barrier between the pre-fibrillar tetramer form and the fibrillar pentamer in the Aβ40 aggregation landscape disappears for Aβ42, suggesting that the Aβ42 tetramer has a more diverse structural range. To further compare the landscapes, we develop a cluster analysis based on the structural similarity between configurations and use it to construct an oligomerization map that captures the paths of easy interconversion between different but structurally similar states of oligomers for both species. A taxonomy of the oligomer species based on β-sheet stacking topologies is proposed. The comparison of the two oligomerization maps highlights several key differences in the landscapes that can be attributed to the two additional C-terminal residues that Aβ40 lacks. In general, the two terminal residues strongly stabilize the oligomeric structures for Aβ42 relative to Aβ40, and greatly facilitate the conversion from pre-fibrillar trimers to fibrillar tetramers.
24 107/1 水環系 陳俊成 副教授 期刊論文 發佈 Theoretical and experimental studies of direct contact membrane distillation modules with inserting W-shaped carbon-fiber spacers , [107-1] 摘要:
25 107/1 化學系 蔡旻燁 助理教授 期刊論文 發佈 PAGE4 and Conformational Switching: Insights from Molecular Dynamics Simulations and Implications for Prostate Cancer , [107-1] 摘要:Prostate-associated gene 4 (PAGE4) is an intrinsically disordered protein implicated in prostate cancer. Thestress-response kinase homeodomain-interacting protein kinase 1 (HIPK1) phosphorylates two residues in PAGE4, serine 9 and threonine 51. Phosphorylation of these two residues facilitates the interaction of PAGE4 with activator protein-1 (AP-1) transcription factor complex to potentiate AP-1's activity. In contrast, hyperphosphorylation of PAGE4 by CDC-like kinase 2 (CLK2) attenuates this interaction with AP-1. Small-angleX-ray scattering and single-molecule fluorescence resonance energy transfer measurements have shown that PAGE4 expands upon hyperphosphorylation and that this expansion is localized to its N-terminal half. To understand the interactions underlying this structural transition, we performed molecular dynamics simulations using Atomistic AWSEM, a multi-scale molecular model that combines atomistic and coarse-grained simulation approaches. Our simulations show that electrostatic interactions drive transient formation of an N-terminal loop, the destabilization of which accounts for the dramatic change in size upon hyperphosphorylation. Phosphorylation also changes the preference of secondary structure formation of the PAGE4 ensemble, which leads to a transition between states that display different degrees of disorder. Finally, we construct a mechanism-based mathematical model that allows us to capture the interactions ofdifferent phosphoforms of PAGE4 with AP-1 and its downstream target, the androgen receptor (AR)—a key therapeutic target in prostate cancer. Our model predicts intracellular oscillatory dynamics of HIPK1-PAGE4, CLK2-PAGE4, and AR activity, indicating phenotypic heterogeneity in an isogenic cell population. Thus, conformational switching of PAGE4 may potentially affect the efficiency of therapeutically targeting AR activity.
26 106/2 數學系 徐祥峻 助理教授 期刊論文 發佈 Fixed points of the evacuation of maximal chains on Fuss shapes , [106-2] 摘要:
27 104/1 數學系 徐祥峻 助理教授 期刊論文 發佈 Max-coloring of vertex-weighted graphs , [104-1] 摘要:
28 103/1 數學系 徐祥峻 助理教授 期刊論文 發佈 Graphs with small balanced decomposition numbers , [103-1] 摘要:
29 101/1 數學系 徐祥峻 助理教授 期刊論文 發佈 Parity and strong parity edge-colorings of graphs , [101-1] 摘要:
30 100/2 數學系 徐祥峻 助理教授 期刊論文 發佈 First-fit chromatic numbers of d-degenerate graphs , [100-2] 摘要:
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