教師資料查詢 | 類別: 期刊論文 | 教師: 廖康伶 KANG-LING LIAO (瀏覽個人網頁)

標題:A lattice model on somitogenesis of zebrafish
學年101
學期1
出版(發表)日期2012/11/01
作品名稱A lattice model on somitogenesis of zebrafish
作品名稱(其他語言)
著者Kang-Ling Liao; Chih-Wen Shih
單位
出版者
著錄名稱、卷期、頁數Discrete and Continuous Dynamical Systems - Series B, No. 17, 2789-2814.
摘要Somitogenesis is the process of the development of somites which are segmental structure in vertebrate embryos. This process depends on the expression of segmentation clock genes. In this investigation, we consider lattice systems which describe the kinetics of the chief segmentation clock genes in zebrafish under negative feedback regulation with delay through interaction with the Delta-Notch signaling among neighboring cells. We first derive the analytical theories for the oscillation-arrested and synchronous oscillation in an autonomous lattice model. Based on the parameter regimes in the theories, we design suitable gradients of degradation rates and delays in a non-autonomous lattice model. Such a lattice system can generate synchronous oscillations, oscillatory traveling waves, oscillation slowing down, oscillation-arrested, and high-low expression levels. We further distinguish between different gradient structures which lead to normal and abnormal segmentations respectively and connect these structures to the dynamical regimes in the cell-cell model.
關鍵字Somitogenesis; lattice model; oscillation-arrested; synchronous oscillation; traveling wave
語言英文(美國)
ISSN
期刊性質國外
收錄於SCI;
產學合作
通訊作者Chih-Wen Shih
審稿制度
國別美國
公開徵稿
出版型式,電子版
相關連結
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