期刊論文
| 學年 | 108 |
|---|---|
| 學期 | 1 |
| 出版（發表）日期 | 2020-01-09 |
| 作品名稱 | Synthesis of N-Heterocycles via Transition-Metal-Catalyzed Tandem Addition/ Cyclization of a Nitrile |
| 作品名稱（其他語言） | |
| 著者 | Jen-Chieh Hsieh（謝仁傑）; Haw-Lih Su |
| 單位 | |
| 出版者 | |
| 著錄名稱、卷期、頁數 | Synthesis 52(6), p.819–833 |
| 摘要 | The diverse methodologies to synthesize N-heterocycles through transition-metal-catalyzed cascade addition/cyclization of a nitrile are discussed in this review. Aspects relating to three types of transition-metal-catalyzed addition of a nitrile with subsequent cyclization include (1) a transition-metal acting as a Lewis acid to accelerate the nucleophilic addition of a nitrile, (2) the late-transition-metal-catalyzed 1,2-insertion of a nitrile, and (3) an in situ generated radical by transition-metal catalysis to implement a radical addition/cyclization tandem reaction. Applications for the synthesis of natural alkaloids, their derivatives, and some bioactive compounds are also summarized herein. |
| 關鍵字 | transition-metal-catalyzed;nitrile addition;cyclization;N-heterocycles;natural alkaloids |
| 語言 | en |
| ISSN | 1437-210X |
| 期刊性質 | 國外 |
| 收錄於 | SCI |
| 產學合作 | |
| 通訊作者 | |
| 審稿制度 | 否 |
| 國別 | DEU |
| 公開徵稿 | |
| 出版型式 | ,電子版 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/120974 ) |