期刊論文

標題 In vitro α-glucosidase and α-amylase inhibition, and in vivo anti-hyperglycemic effects of Psidium littorale Raddi leaf extract
學年 106
學期 2
出版(發表)日期 2018/03/01
作品名稱 In vitro α-glucosidase and α-amylase inhibition, and in vivo anti-hyperglycemic effects of Psidium littorale Raddi leaf extract
作品名稱(其他語言)
著者 Nguyen QV; Wang SL; Nguyen AD
單位
出版者
著錄名稱、卷期、頁數 Research on Chemical Intermediates 44(3), p.1745-1753
摘要 Guava, belonging to family Myrtaceae, is widely grown in tropical countries. Different parts of guava are reported to have long been used in folk medicine. In this study, the in vitro and in vivo anti-hyperglycemic activities of Psidium littorale Raddi leaves extract were investigated. The results indicated that the leaf extract demonstrates relatively high intestinal a-glucosidase inhibitory activity in rats, twice as high as acarbose. In addition, the extract also induced lowering fasting blood glucose levels in streptozotocin- induced diabetic rats at the dose of 150 mg/kg body weight, and without any effect on normal rats. Moreover, the extract did not significantly induce body weight loss in rats. The results suggest that P. littorale Raddi may prove to be useful in treating diabetes in humans.
關鍵字 Antidiabetic;Psidium littorale Raddi;DPPH;α-amylase;α-glucosidase
語言 英文
ISSN 0922-6168
期刊性質 國外
收錄於 SCI;
產學合作
通訊作者
審稿制度
國別 美國
公開徵稿
出版型式 ,電子版