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標題
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Tyrosinase inhibitors and insecticidal materials produced by Burkholderia cepacia using squid pen as the sole carbon and nitrogen source |
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學年
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102 |
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學期
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2 |
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出版（發表）日期
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2014/07/01 |
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作品名稱
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Tyrosinase inhibitors and insecticidal materials produced by Burkholderia cepacia using squid pen as the sole carbon and nitrogen source |
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作品名稱（其他語言）
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|
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著者
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Hsua, Chia-Hao; Nguyenb, Anh Dzung; Chen, Yung-Wei; Wang, San-Lang |
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單位
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淡江大學化學學系 |
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出版者
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Dordrecht: Springer Netherlands |
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著錄名稱、卷期、頁數
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Research on Chemical Intermediates 40(6), pp.2249-2258 |
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摘要
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Reports of tyrosinase inhibitors from microorganisms are rare. A tyrosinase inhibitor- and insecticidal materials-producing bacterium, strain TKU026, was isolated from Taiwanese soil and identified as Burkholderia cepacia. Among the tested chitin-containing materials, squid pen best enhanced the production of tyrosinase inhibitors and insecticidal materials. The tyrosinase inhibitory activity (5000 U/mL) and insecticidal activity (81%) against Drosophila larvae was maximised after cultivation on 1% squid-pen containing medium for three days. The tyrosinase inhibitory activity persisted even when the culture was treated with acidic or alkaline conditions of pH 3 or 11. The activities of both tyrosinase inhibitors and insecticide remained at 100%, even after treatment at 100℃ for 30 min. The culture supernatant after three days of cultivation also showed antifungal activity against Aspergillus fumigatus and Fusarium oxysporum with maximal activities of 100% and 80%, respectively, but no antibacterial activity against Escherichia coli was observed. The tyrosinase inhibitors were assumed to be polyphenolic compounds according to the results of chromatography. |
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關鍵字
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Tyrosinase inhibitor;Squid pen;Insecticide;Burkholderia cepacia |
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語言
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英文 |
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ISSN
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1568-5675 |
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期刊性質
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國外 |
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收錄於
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SCI; |
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產學合作
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通訊作者
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Wang, San-Lang |
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審稿制度
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是 |
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國別
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荷蘭 |
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公開徵稿
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出版型式
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,電子版,紙本 |