期刊論文

學年 96
學期 1
出版(發表)日期 2008-01-01
作品名稱 Synthesis of a New Family of Aminocyclitols from D-(-)-Quinic acid
作品名稱(其他語言)
著者 Shih, Tzenge-lien; Li, Heng-Yi; Ke, Ming-Shin; Kuo, Wei-Shen
單位 淡江大學化學學系
出版者 Philadelphia: Taylor & Francis Inc.
著錄名稱、卷期、頁數 Synthetic Communications 38(23), pp.4139-4149
摘要 In continuation of our interest in the synthesis of glycosidase inhibitors, we report herein an efficient synthesis of three new polyhydroxylated amino cyclohexane derivatives (aminocyclitols) that may potentially possess important biological activities. The key step involved the highly stereoselective dihydroxylation of protected azido cyclohexene derivatives 5, 9, and 15, which were easily red from D-(-)-quinic acid. The subsequent hydrogenation step was conducted under acidic conditions to provide the target molecules in an efficient manner with high overall yields.
關鍵字
語言 en
ISSN 0039-7911; 1532-2432
期刊性質 國外
收錄於 SCI
產學合作
通訊作者
審稿制度
國別 USA
公開徵稿
出版型式 紙本
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